L-arginine is a semi-essential amino acid involved in numerous areas of human biochemistry, including ammonia detoxification, hormone secretion, and immune modulation. Arginine is also well known as a precursor to nitric oxide (NO). Ornithine is an important component of the urea cycle, also called the ornithine cycle, a process that removes excess nitrogen from the body. When combined with arginine, ornithine is used in building muscles and developing muscle mass. It increases growth hormones and produces insulin in the body, two important substances needed in muscle recovery during intense physical exercise and bodybuilding.
Ornithine is used to enhance brain activity especially in patients suffering from liver diseases.
Arginine/Ornithine and HGH
The human growth hormone, HGH, is an immensely versatile hormone that affects many of our bodily functions; including bone growth, increasing muscle mass, and decreasing fat mass. However, this hormone does not work alone, studies have shown that L-Arginine and Ornithine are an important factor in ensuring that HGH levels are adequately used by the body.
But what are these two unusually named proteins and why are they so important? An overview of the proteins’ structure, where they are found in nature, and how they affect each other, will help give you a better understanding of these proteins.
What is L-Arginine?
Arginine is an amino acid synthesized with the assistance of another amino acid; citruline both of which are involved in the urea cycle and thus have a strong Nitrogen base. Arginine is found throughout the body and is produced at the cellular level of many mammals. Therefore, because most people can produce Arginine, it is considered an unessential amino acid, but, poor nutrition or disease usually require arginine supplements. Arginine can be found in most fish, meat, dairy, wheat germ, and nut products. Arginine has been found to have the many benefits on the body including:-
- -wound healing
- -assisting with removing uric acid waste
- -interacting with human growth hormone to promote muscle mass and decrease fat mass
- -have a positive effect in keeping a healthy heart
What is Ornithine?
Ornithine is an amino acid invovled in the urea cycle is used a pseudo-catalyst to help get rid of nitrogen in the body. It is important to note that ornithine is required for the synthesis of Arginine, thus, even though ornithine is part of the 20 essential amino acids, it is still very important to the body.
Ornithine can be produced by the body, however, deficiencies can sometimes be found in women who are pregnant, vegetarians, and malnurished individuals. Ornithine can be found in most meat, fish, dairy, and eggs. Ornithine has been found to have many benefits on the body including;
-interacting with the human growth hormone
-having an antifatigue effect on people who exercise
-possible wound healing properties
Possible side effects of both
As with anything, moderation is the important when taking supplements. Because arginine and ornithine are produced in the body, it is not usually suggested that high doses of either should be taken by anyone. Side effects include;
Side effects of either protein are not severe and can be dealt with by stopping your supplement intake.
Human growth hormone boosters:- A quick search on the internet for either of these two proteins will bring up many retailers. However, buyers who are looking to supplement their program with HGH for optimum results should think about investing in a product that combines L-Arginine and Ornithine in the most natural way possible to promote bone growth, increase muscle mass, and decrease fat mass.
Arginine was first isolated from a lupin seedling extract in 1886 by the German chemist Ernst Schultze 5 it has an a-amino group (which can be within the protonated -NH3+ form under biological conditions), an a-carboxylic acid group (that is within the deprotonated -COO- form under biological conditions), and a side chain of a 3-carbon aliphatic straight chain capped by a complex guanidinium , classifying it as a charged (at physiological pH), aliphatic amino acid.
Intake of arginine by trained people can strengthen their immune system, thereby allowing them to train harder and also to avoid the unpleasant consequences of overtraining.
Ornithine is certainly one regarding the three amino acids active in the Urea cycle, alongside L-Arginine and L-Citrulline ; this amino acids generally seems to reduce elevated ammonia levels when supplemented, and preliminary evidence suggests an ergogenic role due to this.
While the ornithine/growth hormone connection is disputed by some, I know for a fact that maintaining lean muscle tissue is easier when I am supplementing with ornithine. The precautions continue to be the same with ornithine as stated previously for arginine. It really is drawn in combination with arginine and sometimes even alone as it does exactly the same function as arginine- raises nitric oxide levels which in turn have many biological implications. Ornithine and Arginine are both fairly cheap and simple to find in capsule or powdered form.
But if you have a history of certain health conditions, your doctor may recommend taking arginine supplements.
Arginine and Ornithine combines two essential amino acids into one optimal supplement. However, this ability is genetically masked by the feedback regulatory mechanisms operating in the arginine biosynthetic pathway. Among the best benefits associated with arginine supplementation is that it effectively targets stomach fat and gets rid from it. Therefore some recommend taking L-citrulline either alone or in combination with arginine at a dose of 6-8g citrulline malate. As an example, females seem to demonstrate a better amount of growth hormone release after taking arginine, ornithine and lysine supplements than males.MORE INFORMATION